Side effects may be different for different people - including the time it may take for people to experience them. When should I expect to feel side effects after my second shot? Nearly 80% of women reported adverse events versus about 20% of men. And in some studies, women were more likely to report side effects to the COVID-19 vaccines than men. Several factors can affect how your immune system reacts to a vaccine, including:įor example, infants and toddlers are less likely to have reactions at the vaccine injection site but more likely to develop a fever than adults. Your immune system’s response to the vaccine will depend on your medical history and the type of vaccine. Are some people more likely to have side effects from the Moderna and Pfizer vaccine? Below we’ll review a few other factors that might influence your likelihood of experiencing side effects. Similarly, joint pain was more common after the second shot, going from about 9% (first dose) to 26% (second dose).ĭuring the Pfizer and Moderna clinical trials, side effects were reported more frequently in younger people getting the vaccine. In the first few months after the Pfizer and Moderna vaccines were authorized, 70% to 75% of people reported this side effect after getting either dose.Īdditionally, 50% of people reported systemic side effects (e.g., fatigue, headache, or muscle pain) after their first dose, which jumped to about 70% after the second dose.Ĭhills and fever, which were reported by only about 9% of people after their first dose, went up to about 30% after the second dose. Most people may experience at least one side effect after getting their dose - the most common being an injection site reaction (e.g., pain, swelling, or redness). How many people experience Pfizer and Moderna side effects? More serious side effects, like a severe allergic reaction and myocarditis (heart inflammation) or pericarditis (heart lining inflammation), are very rare. Because of this, you may experience similar side effects with either brand, but they may be more noticeable after the second shot. The Pfizer and Moderna COVID-19 vaccines are the same type of vaccine - called messenger RNA (mRNA) vaccines. Pfizer and Moderna side effects after the second COVID-19 vaccine shot However, new data suggests a second dose of this vaccine can help provide additional protection against COVID-19. The Johnson & Johnson vaccine is a single shot. For more information on who currently should receive a third dose, click or tap here. A third dose is not currently required in other people who are fully vaccinated. The FDA has also authorized a third COVID-19 vaccine dose for select individuals with lower immunity and people over age 65. For both vaccines, you need both doses to be fully vaccinated. For the Moderna vaccine, you need to wait 28 days. For the Pfizer vaccine, you need to wait 21 days after the first dose to get the second dose. Which COVID-19 vaccines require a second dose?īoth the Pfizer and Moderna COVID-19 vaccines require two doses. We’ll take a look at how the immune system responds to vaccines, what the Pfizer and Moderna vaccine side effects are, and why they tend to be worse after the second shot. This phenomenon has to do with how vaccines help your immune system fight off infection. Many people have wondered why they have more intense side effects after getting the second shot of the Pfizer or Moderna COVID-19 vaccine.
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